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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DUOX1
All Species:
20
Human Site:
S199
Identified Species:
40
UniProt:
Q9NRD9
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NRD9
NP_787954.1
1551
177235
S199
F
S
R
G
Q
L
A
S
G
P
D
P
A
F
P
Chimpanzee
Pan troglodytes
XP_001163196
1551
177072
S199
F
S
G
G
Q
L
A
S
G
P
D
P
A
F
P
Rhesus Macaque
Macaca mulatta
XP_001111340
1551
176921
S199
F
S
G
G
Q
L
A
S
G
P
D
P
A
F
P
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
NP_001092767
1551
177113
S199
F
S
G
G
Q
L
A
S
G
P
D
P
A
F
P
Rat
Rattus norvegicus
Q8CIY2
1551
177179
S199
F
S
G
G
Q
L
A
S
G
P
D
P
A
F
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518643
1547
175433
A206
F
S
G
G
Q
L
A
A
G
P
D
P
D
F
P
Chicken
Gallus gallus
XP_425053
1523
173782
S186
F
S
N
G
Q
L
A
S
G
P
G
G
H
V
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001919394
1322
150039
A66
P
R
R
I
S
T
T
A
M
S
G
Q
S
G
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VQH2
1475
170768
N186
D
G
K
L
P
V
R
N
T
M
R
V
P
L
F
Honey Bee
Apis mellifera
XP_624355
1492
172466
M190
F
K
N
G
S
L
L
M
E
P
T
R
K
F
P
Nematode Worm
Caenorhab. elegans
O61213
1497
170397
E196
F
K
Q
G
R
L
A
E
G
V
P
G
Y
P
P
Sea Urchin
Strong. purpuratus
NP_001118237
1671
189876
D281
F
K
D
G
R
L
A
D
N
G
E
I
G
G
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
96.7
N.A.
N.A.
91
90.1
N.A.
73.9
65.1
N.A.
47.1
N.A.
39.9
40.3
34.3
41.6
Protein Similarity:
100
99.4
97.8
N.A.
N.A.
95
94.4
N.A.
84.4
78.4
N.A.
61.7
N.A.
58
60.2
55.9
59.3
P-Site Identity:
100
93.3
93.3
N.A.
N.A.
93.3
93.3
N.A.
80
66.6
N.A.
6.6
N.A.
0
40
40
26.6
P-Site Similarity:
100
93.3
93.3
N.A.
N.A.
93.3
93.3
N.A.
86.6
66.6
N.A.
20
N.A.
20
40
53.3
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
75
17
0
0
0
0
42
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
0
9
0
0
0
0
9
0
0
50
0
9
0
0
% D
% Glu:
0
0
0
0
0
0
0
9
9
0
9
0
0
0
9
% E
% Phe:
84
0
0
0
0
0
0
0
0
0
0
0
0
59
9
% F
% Gly:
0
9
42
84
0
0
0
0
67
9
17
17
9
17
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% H
% Ile:
0
0
0
9
0
0
0
0
0
0
0
9
0
0
0
% I
% Lys:
0
25
9
0
0
0
0
0
0
0
0
0
9
0
0
% K
% Leu:
0
0
0
9
0
84
9
0
0
0
0
0
0
9
9
% L
% Met:
0
0
0
0
0
0
0
9
9
9
0
0
0
0
0
% M
% Asn:
0
0
17
0
0
0
0
9
9
0
0
0
0
0
0
% N
% Pro:
9
0
0
0
9
0
0
0
0
67
9
50
9
9
75
% P
% Gln:
0
0
9
0
59
0
0
0
0
0
0
9
0
0
0
% Q
% Arg:
0
9
17
0
17
0
9
0
0
0
9
9
0
0
0
% R
% Ser:
0
59
0
0
17
0
0
50
0
9
0
0
9
0
0
% S
% Thr:
0
0
0
0
0
9
9
0
9
0
9
0
0
0
0
% T
% Val:
0
0
0
0
0
9
0
0
0
9
0
9
0
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _